Additional Information

Description

Dihydroergotamine 1 mg/mL solution (10 mL) is a potent ergot alkaloid used primarily for the acute treatment of migraine headaches and cluster headaches. It is a selective serotonin receptor agonist and acts by constricting dilated blood vessels in the brain, thereby reducing the pain and associated symptoms of these headache types. Its mechanism also involves inhibiting the release of pro-inflammatory neuropeptides, contributing to its therapeutic effects.

This solution is typically administered via subcutaneous or intravenous injection and is most effective when used during the onset of a headache. It provides rapid relief from moderate to severe headache pain and can be used as part of a comprehensive migraine management plan. The solution is packaged in a 10 mL vial, allowing for precise dosing according to the patient's needs.

Dihydroergotamine 1 mg/mL should not be used in patients with certain cardiovascular conditions, such as uncontrolled hypertension or coronary artery disease, due to the potential for serious vasoconstrictive effects. It is essential to monitor for adverse reactions such as nausea, dizziness, or chest pain during treatment.